By Th. Büchner (auth.), W. Hinterberger, A. J. Barrett, K. Lechner, E. Deutsch (eds.)
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Extra resources for 11th Annual meeting of the EBMT: European Cooperative Group for Bone Marrow Transplantation
Baumgartner I, E. A. Bleher 3 , G. Brun del Re 2 , U. Bucher 2 , H. Frei\ R. Greiner 3 , A. Hirt 4 , P. Imbach \ Annette Lüthy I, Angelika C. Stern 2 , and H. P. Wagner 1 • 4 1 2 3 4 Department of Pediatrics Central Hematology Labaratory Clinic for Radiotherapy, Inselspital, Bern Institute for Clinical and Experimental Cancer Research ofthe University, Bern, Switzerland As the number of pati ents s u r vivi ng a ft er autol ogaus bone marrow transp l antation (ABMT ) i s in creasing late effects of s uch procedures become a question o f major concern.
Skeletal x-ray survey was negative for osteolytic lesions. v. on Days- 4 and- 3) and TBI ( 1000 rads in a single fraction at a dose ture (3,4) appear to suggest thc potential usefulness of BMT in MM. Wc believe that this procedure descrves strong consideration in young patients, given the disappointingly slow progresses in the conventional treatment of MM and the ominous prognosis of thc discase. REFERENCES l. , Tura S. (1983) - High-dose melphalan for multiple myeloma. Lancet ii: 1194. 2. bone marrow transplantation.
Age and Sex Distribution HD NHL (} 1 1 year 1 3 1-15 19 32 15-30 8 33 30-45 1 12 45-60 20 54 Males 9 25 Fernales Histology HD HD HD HD HD NS gd. prog. NS bd. prog. Status at ABMT: D. CR PR A B 1 NHL NHL NHL NHL int. Brk. lym. oth. grd. grd. grd. grd. D MC 9 5 1 0 1 9 4 110 22 13 10 51 14 (D=diagnosis, A=responding relapse, B=resistant relapse) Inrounology 34 Unknawn 20 (NHL ~nly)T-cell 16 B-cell 3 Null 8 True histiocytic Conditioning Chemotherapy: HD 28 NHL 62 1 NHL 19 HD Chemo & DXR: Purging had marrow purged 10/llO with T monoclonal l with 4 HC 2 with Asta 7 7 Results Haemopoietic recovery is shown in relation to dose in Table 1.
11th Annual meeting of the EBMT: European Cooperative Group for Bone Marrow Transplantation by Th. Büchner (auth.), W. Hinterberger, A. J. Barrett, K. Lechner, E. Deutsch (eds.)